The Medtronic Freestyle is a stentless porcine valve fixed in glutaraldehyde at zero pressure and treated with α-aminoleic acid, an anticalcification agent probably acting through the mechanism of detoxification. As with other stentless valves, it was introduced to improve hemodynamics in valve replacement for aortic stenosis by reducing the transvalvular gradient and thus favoring regression of left ventricular hypertrophy. This issue of the journal reports a pathological study on nine explants
Achilles' heel of stentless porcine valves
THIENE, GAETANO;VALENTE, MARIALUISA
2007
Abstract
The Medtronic Freestyle is a stentless porcine valve fixed in glutaraldehyde at zero pressure and treated with α-aminoleic acid, an anticalcification agent probably acting through the mechanism of detoxification. As with other stentless valves, it was introduced to improve hemodynamics in valve replacement for aortic stenosis by reducing the transvalvular gradient and thus favoring regression of left ventricular hypertrophy. This issue of the journal reports a pathological study on nine explants
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