Silica nanoparticles (about 15 nm diameters), which contain a derivative of 6-methoxy-8-(p-toluensulfonamido)-quinoline (TSQ) as a Zn-II fluorescent probe covalently linked to the silica network, were prepared and studied as Zn-II fluorescent chemosensors. The systems selectively detect Zn-II ions in water rich solutions with a submicromolar sensitivity: 0.13 mu M concentrations of Zn-II can be measured with the only interference of Cull and Cd-II ions. Compared with free TSQ, the nanoparticles based systems have the advant-age that they can be employed in aqueous solutions without aggregation problems while at the same time, they maintain a similar Zn-II affinity and sensing ability. Addition of a second, substrate insensitive, fluorophore to the particles leads to the realization of a ratiometric sensor.
Silica nanoparticles for fluorescence sensing of Zn-II: Exploring the covalent strategy
MANCIN, FABRIZIO;TONELLATO, UMBERTO
2007
Abstract
Silica nanoparticles (about 15 nm diameters), which contain a derivative of 6-methoxy-8-(p-toluensulfonamido)-quinoline (TSQ) as a Zn-II fluorescent probe covalently linked to the silica network, were prepared and studied as Zn-II fluorescent chemosensors. The systems selectively detect Zn-II ions in water rich solutions with a submicromolar sensitivity: 0.13 mu M concentrations of Zn-II can be measured with the only interference of Cull and Cd-II ions. Compared with free TSQ, the nanoparticles based systems have the advant-age that they can be employed in aqueous solutions without aggregation problems while at the same time, they maintain a similar Zn-II affinity and sensing ability. Addition of a second, substrate insensitive, fluorophore to the particles leads to the realization of a ratiometric sensor.
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