Compartmental models are a class of dynamic, i.e., differential equation, models derived from mass balance considerations which are widely used for quantitative studying the kinetics of materials in physiologic systems. Materials can be either exogenous, such as a drug or a tracer, or endogenous, such as a substrate or a hormone, and kinetics include processes such as production, distribution, transport, utilization, and substrate-hormone control interactions.
Compartmental Models of Physiologic Systems.
SPARACINO, GIOVANNI;M. P. SACCOMANI;
2006
Abstract
Compartmental models are a class of dynamic, i.e., differential equation, models derived from mass balance considerations which are widely used for quantitative studying the kinetics of materials in physiologic systems. Materials can be either exogenous, such as a drug or a tracer, or endogenous, such as a substrate or a hormone, and kinetics include processes such as production, distribution, transport, utilization, and substrate-hormone control interactions.
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