PINNA, LORENZO
 Distribuzione geografica
Continente #
NA - Nord America 29.548
AS - Asia 7.846
EU - Europa 5.471
AF - Africa 2.060
SA - Sud America 1.655
OC - Oceania 217
Continente sconosciuto - Info sul continente non disponibili 99
AN - Antartide 1
Totale 46.897
Nazione #
US - Stati Uniti d'America 28.467
SG - Singapore 2.291
CN - Cina 1.901
HK - Hong Kong 1.154
BR - Brasile 1.015
DE - Germania 771
FI - Finlandia 737
VN - Vietnam 460
SE - Svezia 443
IT - Italia 351
UA - Ucraina 291
PL - Polonia 286
GB - Regno Unito 260
RU - Federazione Russa 257
FR - Francia 256
NL - Olanda 175
IN - India 152
RO - Romania 101
CI - Costa d'Avorio 100
IE - Irlanda 99
AR - Argentina 98
TR - Turchia 98
AT - Austria 80
IQ - Iraq 79
ES - Italia 78
ID - Indonesia 78
MX - Messico 77
TT - Trinidad e Tobago 76
CA - Canada 75
ZA - Sudafrica 74
CL - Cile 73
RS - Serbia 73
UY - Uruguay 72
CZ - Repubblica Ceca 71
GT - Guatemala 71
AO - Angola 70
AL - Albania 65
BZ - Belize 65
MA - Marocco 65
TJ - Tagikistan 65
IL - Israele 64
JP - Giappone 64
ME - Montenegro 64
PY - Paraguay 64
AE - Emirati Arabi Uniti 63
EC - Ecuador 63
HN - Honduras 63
JM - Giamaica 63
IR - Iran 62
KZ - Kazakistan 62
MW - Malawi 62
PS - Palestinian Territory 60
SK - Slovacchia (Repubblica Slovacca) 60
ZM - Zambia 60
JO - Giordania 59
MU - Mauritius 59
MY - Malesia 59
EG - Egitto 58
KR - Corea 58
LV - Lettonia 58
VE - Venezuela 58
BY - Bielorussia 57
DZ - Algeria 57
GF - Guiana Francese 57
HU - Ungheria 57
KE - Kenya 57
PK - Pakistan 57
PT - Portogallo 57
LY - Libia 56
NI - Nicaragua 56
SA - Arabia Saudita 56
TN - Tunisia 56
CO - Colombia 55
GE - Georgia 55
MN - Mongolia 55
TH - Thailandia 55
BB - Barbados 54
BG - Bulgaria 54
CR - Costa Rica 54
CW - ???statistics.table.value.countryCode.CW??? 54
EE - Estonia 54
KG - Kirghizistan 54
MR - Mauritania 54
NO - Norvegia 54
NP - Nepal 54
BF - Burkina Faso 53
CV - Capo Verde 53
DO - Repubblica Dominicana 53
LA - Repubblica Popolare Democratica del Laos 53
BE - Belgio 52
ET - Etiopia 52
GH - Ghana 52
MD - Moldavia 52
NZ - Nuova Zelanda 52
AZ - Azerbaigian 51
CH - Svizzera 51
IS - Islanda 51
MZ - Mozambico 51
SN - Senegal 51
UZ - Uzbekistan 51
Totale 44.460
Città #
Fairfield 4.317
Woodbridge 2.998
Houston 2.439
Ashburn 2.221
Chandler 2.176
Ann Arbor 2.030
Wilmington 1.650
Cambridge 1.572
Seattle 1.517
Singapore 1.389
Jacksonville 1.141
Hong Kong 1.090
Boardman 593
Princeton 589
Beijing 475
San Diego 433
Santa Clara 346
Des Moines 292
Nanjing 270
Helsinki 262
Medford 233
Bytom 215
Dong Ket 205
Los Angeles 154
Roxbury 123
Munich 116
Guangzhou 115
Shenyang 103
New York 100
Chicago 99
Padova 98
Abidjan 94
Nanchang 90
Ho Chi Minh City 84
Hebei 81
Dublin 75
São Paulo 72
Jinan 65
Turku 65
Changsha 64
Dushanbe 63
Luanda 63
Vienna 61
Hanoi 60
Lusaka 59
Montevideo 59
Norwalk 59
Amman 56
Dallas 55
Jiaxing 55
Managua 55
Tianjin 55
London 54
Ulan Bator 54
Hefei 53
Podgorica 52
Bridgetown 51
Dakar 51
Buffalo 49
Accra 48
Nouakchott 48
Baku 47
Libreville 47
Lilongwe 47
Tashkent 47
Vientiane 47
Noumea 46
Bishkek 45
Praia 45
Nairobi 44
Willemstad 44
Belgrade 43
Djibouti 43
Addis Ababa 42
Bamako 42
Minsk 42
Phnom Penh 42
Riga 42
Yerevan 42
Castries 41
Cayenne 41
Guatemala City 41
Antananarivo 40
Cotonou 40
Kingston 40
Ouagadougou 40
Conakry 39
Maputo 39
Niamey 39
Redwood City 39
Dar es Salaam 38
Kampala 37
Mamoudzou 37
Panama City 37
Havana 36
Nassau 36
Chisinau 35
Harare 35
San José 35
Tripoli 35
Totale 32.808
Nome #
"Genuine" Casein Kinase: The False Sister of CK2 That Phosphorylates Secreted Proteins at S-X-E/pS Motifs 263
ATP Site-Directed Inhibitors of Protein Kinase CK2: An Update 243
A Comparative Analysis and Review of lysyl Residues Affected by Post-translational Modifications 228
Protein kinase CK2 potentiates translation efficiency by phosphorylating eIF3j at Ser127. 214
Inhibition of Protein Kinase CK2 by Flavonoids and Tyrphostins. A Structural Insight. 209
Biochemical and three-dimensional-structural study of the specific inhibition of protein kinase CK2 by [5-oxo-5,6-dihydroindolo-(1,2-a)quinazolin-7-yl]acetic acid (IQA) 208
Protein kinase CK2 phosphorylates and upregulates Akt/PKB 204
4-Fluoroproline derivative peptides: Effect on PPII conformation and SH3 affinity 203
A proteomics analysis of CK2β(-/-) C2C12 cells provides novel insights into the biological functions of the non-catalytic β subunit 203
Re-evaluation of protein kinase CK2 pleiotropy: new insights provided by a phosphoproteomics analysis of CK2 knockout cells 200
A journey through the cytoskeleton with protein kinase CK2 198
Phosphorylation and activation of the atypical kinase p53-related protein kinase (PRPK) by Akt/PKB 198
Identification of ellagic acid as potent inhibitor of protein kinase CK2: a successful example of a virtual screening application. 193
A "SYDE" effect of hierarchical phosphorylation: possible relevance to the cystic fibrosis basic defect. 188
Dependence of HSP27 cellular level on protein kinase CK2 discloses novel therapeutic strategies 186
Phosphorylation of the Saccharomyces cerevisiae Grx4p glutaredoxin by the Bud32p kinase unveils a novel signaling pathway involving Sch9p, a yeast member of the Akt/PKB subfamily. 184
2-Dimethylamino-4,5,6,7-tetrabromo-1H-benzimidazole: a novel powerful and selective inhibitor of protein kinase CK2 184
A structural insight into CK2 inhibition 183
Dephosphorylation and inactivation of Akt/PKB is counteracted by protein kinase CK2 in HEK 293T cells 182
Basic residues in the 74-83 and 191-198 segments of protein kinase CK2 catalytic subunit are implicated in negative but not in positive regulation by the beta-subunit 179
Comparative study of mitochondrial and cytosol protein kinase activities. 179
Structure-function analysis of yeast piD261/Bud32, an atypical protein kinase essential for normal cell life. 178
Chronic lymphocytic leukemia B cells contain anomalous Lyn tyrosine kinase, a putative contribution to defective apoptosis. 178
A protein kinase CK2 site flanking the nuclear targeting signal enhances nuclear transport of human cytomegalovirus ppUL44 176
From phosphoproteins to phosphoproteomes: A historical account 174
Glycolytic enzyme expression and pyruvate kinase activity in cultured fibroblasts from type 1 diabetic patients with and without nephropathy. 174
Analysis of the interaction between piD261/Bud32, an evolutionarily conserved protein kinase of Saccharomyces cerevisiae, and the Grx4 glutaredoxin 172
Site specificity of p72syk protein tyrosine kinase. Efficient phosphorylation of motifs recognized by Src homology 2 domains of the Src family 171
Exploiting the repertoire of CK2 inhibitors to target DYRK and PIM kinases 171
Aberrant signalling by protein kinase CK2 in imatinib-resistant chronic myeloid leukaemia cells. Biochemical evidence and therapeutic perspectives 171
The lysine-specific demethylase 1 is a novel substrate of protein kinase CK2 167
Conformational constraints of Tyrosine in Protein Tyrosine Kinase substrates: Information about preferred bioactive side chain orientation 167
Specific monitoring of Syk protein kinase activity by peptide substrates including constrained analogs of tyrosine 167
Aurora-A site specificity: a study with synthetic peptide substrates 166
Inhibition of protein kinase CK2 by condensed polyphenolic derivatives. An in vitro and in vivo study 165
Synthesis and properties of a selective inhibitor of homeodomain-interacting protein kinase 2 (HIPK2). 165
Acidophilic character of yeast piD261/Bud32, a putative ancestor of eukaryotic protein kinases 164
Phosphorylation of cystic fibrosis transmembrane conductance regulator (CFTR) serine-511 by the combined action of tyrosine kinases and CK2: the implication of tyrosine-512 and phenylalanine-508 163
The Replacement of ATP by the Competitive Inhibitor Emodin Induces Conformational Modifications in the Catalytic Site of Protein Kinase CK2 162
Structural requirements for the enzymatic phosphorylation of phosvitin. 161
Cell-permeable dual inhibitors of protein kinases CK2 and PIM-1: structural features and pharmacological potential 161
Inhibition of protein kinase CK2 with the clinical-grade small ATP-competitive compound CX-4945 or by RNA interference unveils its role in acute myeloid leukemia cell survival, p53-dependent apoptosis and daunorubicin-induced cytotoxicity 161
CFTR mutations altering CFTR fragmentation 161
Chimeric peptides as modulators of CK2-dependent signaling: Mechanism of action and off-target effects 160
Bovine prion protein as a modulator of protein kinase CK2 159
Differential phosphorylation of Akt1 and Akt2 by protein kinase CK2 may account for isoform specific functions. 159
Functional homology between yeast piD261/Bud32 and human PRPK: both phosphorylate p53 and PRPK partially complements piD261/Bud32 deficiency 158
Binding interactions of phospho-Htc peptide to c-Fgr SH2 domain 158
A multifunctional network of basic residues confers unique propertiers to protein kinase CK2 156
405 HCV NS5A phosphorylation by CK2 is genotype dependent 156
Specificity of T-cell protein tyrosine phosphatase toward phosphorylated synthetic peptides. 156
Protein kinase CK2 protects multiple myeloma cells from ER stress-induced apoptosis and from the cytotoxic effect of HSP90 inhibition through regulation of the unfolded protein response 156
CK2 regulates in vitro the activity of the yeast cyclin-dependent kinase inhibitor Sic1 155
Biochemical evidence that Saccharomyces cerevisiae YGR262c gene, required for normal growth, encodes a novel Ser/Thr-specific protein kinase 155
A mechanistic design principle for protein tyrosine kinase sensors: Application to a validated cancer target 155
A comparative study of the phosphotyrosyl phosphatase specificity of PP2A and PTP-1B using phosphopeptides and the phosphoproteins p50/HS1, c-Fgr and Lyn 154
Heterogeneity of CK2 phosphorylation sites in the NS5A protein of different hepatitis C virus genotypes. 154
A noncanonical sequence phosphorylated by casein kinase 1 in beta-catenin may play a role in casein kinase 1 targeting of important signaling proteins 154
Different specificities of spleen tyrosine protein kinases for synthetic peptide substrates. 153
Development and exploitation of CK2 inhibitors 153
Sic1 is phosphorylated by CK2 on Ser201 in budding yeast cells 152
Inspecting the structure-activity relationship of protein kinase CK2 inhibitors derived from tetrabromo-benzimidazole 152
Possible implication of the golgi apparatus casein kinase in the phosphorylation of vesicle docking protein p115 ser-940: a study with peptide substrates 152
Isoform specific phosphorylation of p53 by protein kinase CK1 152
An exploration of the effects of constraints on the phosphorylation of synthetic protein tyrosine kinase peptide substrates. 151
Autophosphorylation at the regulatory beta subunit reflects the supramolecular organization of protein kinase CK2 149
An analysis of the substrate specificity of insulin-stimulated protein kinase-1, a mammalian homologue of S6 kinase-II. 149
Developmental phosphoproteomics identifies the kinase CK2 as a driver of Hedgehog signaling and a therapeutic target in medulloblastoma 149
Effects of the CK2 inhibitors CX-4945 and CX-5011 on drug-resistant cells 148
A type-1 casein kinase from yeast phosphorylates both serine and threonine residues of casein. Identification of the phosphorylation sites. 148
The protein kinase CK2 facilitates repair of chromosomal DNA single-strand breaks 147
Structural features underlying the selectivity of the kinase inhibitors NBC and dNBC: role of a nitro group that discriminates between CK2 and DYRK1A 147
ON THE MECHANISM OF MITOCHONDRIAL PHOSPHORYLATION OF PHOSVITIN. 147
The pleiotropic protein kinase CK2 phosphorylates HTLV-1 Tax protein in vitro, targeting its PDZ-binding motif 147
Effects of CK2β subunit down-regulation on Akt signalling in HK-2 renal cells 147
Dephosphorylation of phosphopeptides by calcineurin (protein phosphatase 2B) 146
Assessment of CK2 Constitutive Activity in Cancer Cells 146
Superiority of PLK-2 as α-synuclein phosphorylating agent relies on unique specificity determinants. 146
Synthetic Tyr-phospho and non-hydrolyzable phosphonopeptides as PTKs and TC-PTP inhibitors. 146
The selectivity of inhibitors of protein kinase CK2: an update 145
Urolithin as a converging scaffold linking ellagic acid and coumarin analogues: design of potent protein kinase CK2 inhibitors. 145
Comparative analysis of CK2 expression and function in tumor cell lines displaying sensitivity vs. resistance to chemical induced apoptosis 145
Variable contribution of protein kinases to the generation of the human phosphoproteome: a global weblogo analysis 144
Structural features underlying selective inhibition of protein kinase CK2 by ATP site-directed tetrabromo-2-benzotriazole 144
A study with model substrates of the structure of the sites phosphorylated by rat liver casein kinase TS. 143
Pharmacophore-guided discovery of CDC25 inhibitors causing cell cycle arrest and tumor regression 143
Grp94 is Tyr-phosphorylated by Fyn in the lumen of the endoplasmic reticulum andtranslocates to Golgi in differentiating myoblasts. 142
Endogenous proteinkinase-dependent phosphorylation of rat liver mitochondrial membranes. 142
Understanding protein kinase CK2 mis-regulation upon F508del CFTR expression 142
Proteomic analysis of clonal interstitial aortic valve cells acquiring a pro-calcific profile. 141
Spontaneous autophosphorylation of Lyn tyrosine kinase at both its activation segment and C-terminal tail confers altered substrate specificity 141
Casein kinase: the triple meaning of a misnomer. 140
Matching up Phosphosites to Kinases: A Survey of Available Predictive Programs 140
Unique features of HIV-1 Rev protein phosphorylation by protein kinase CK2 ('casein kinase-2') 140
Hydrophobic Derivatives of Glycopeptide Antibiotics as Inhibitors of Protein Kinases 140
Antennapedia/HS1 chimeric phosphotyrosil peptide: conformational properties, binding capability to c-Fgr SH2 domain and cell permeability 139
Structural and functional analysis of the flexible regions of the catalytic α-subunit of protein kinase CK2. 139
On the possible role of phosphoproteins as iron carriers. 139
Linear and cyclic synthetic peptides related to the main autophosphorylation site of the Src tyrosine kinases as substrates and inhibitors of Lyn. 139
Phosphorylation of structural protein catalyzed by rat-liver mitochondria. 139
Totale 16.368
Categoria #
all - tutte 152.806
article - articoli 141.807
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 514
selected - selezionate 0
volume - volumi 6.368
Totale 301.495


Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/20213.428 0 0 0 289 270 458 180 381 658 346 461 385
2021/20225.442 100 642 900 447 159 237 270 672 195 66 699 1.055
2022/20234.103 792 504 50 564 642 634 1 268 432 21 151 44
2023/20241.628 75 290 186 86 160 179 84 84 36 63 221 164
2024/20256.973 28 537 329 323 974 185 268 549 583 173 1.231 1.793
2025/20269.753 988 2.626 4.239 1.900 0 0 0 0 0 0 0 0
Totale 47.038