BENEDETTI, PIETRO
BENEDETTI, PIETRO
A single mutation in the 729 residue modulates human DNA topoisomerase IB DNA binding and drug resistance.
2008 Losasso, Carmen; Cretaio, Erica; Fiorani, P; D'Annessa, I; Chillemi, G; Benedetti, Pietro
Alterations in linker flexibility suppress DNA topoisomerase I mutant-induced cell lethality
2007 Losasso, Carmen; Cretaio, Erica; Komaraiah, Palle; Luca, Pattarello; MARY ANN, Bjornsti; Benedetti, Pietro
Analysis of Camptothecin resistance in yeast: relevance to cancer therapy.
1998 Benedetti, Pietro; Benchokroun, Y; Houghton, P. J.; Bjornsti, M. A.
Artemisinin Derivatives with Antimelanoma Activity Show Inhibitory Effect against Human DNA Topoisomerase 1
2020 Botta, Lorenzo; Filippi, Silvia; Zippilli, Claudio; Cesarini, Silvia; Mattia Bizzarri, Bruno; Cirigliano, Angela; Rinaldi, Teresa; Paiardini, Alessandro; Fiorucci, Diego; Saladino, Raffaele; Negri, Rodolfo; Benedetti, Pietro
Biologia Molecolare terza edizione
2018 F., Amaldi; Benedetti, Pietro; G., Pesole; P., Plevani
Camptothecin resistance from a single mutation changing glycine 363 of human DNA topoisomerase I to cysteine.
1993 Benedetti, Pietro; Fiorani, P; Capuani, L; Wang, J. C.
Comparative mutational analysis of wild-type and stretched tRNALeu3 gene promoters.
1987 Fabrizio, P; Coppo, A; Fruscoloni, P; Benedetti, Pietro; DI SEGNI G, TOCCHINI VALENTINI G. P.
Disulfide cross-links reveal conserved features of DNA topoisomerase I architecture and a role for the n terminus in clamp closure
2008 Palle, K; Pattarello, Luca; VAN DER MERWE, M; Losasso, Carmen; Benedetti, Pietro; Bjornsti, Ma
Domain Interactions Affecting Human DNA Topoisomerase I Catalysis and Camptothecin Sensitivity. Molecular Phamacology 56:1105-1115 (1999).
1999 Fiorani, P.; Amatruda, Jf; Silvestri, ; Bjornsti, Ma; Butler, Rh; Benedetti, Pietro
Drug-induced stabilization of covalent DNA topoisomerase I-DNA intermediates. DNA cleavage assays
2001 Fiorani, P; Hann, Cl; Benedetti, Pietro; Bjornsti, M.
Effect on DNA relaxation of the single Thr718Ala mutation in human topoisomerase I: a functional and molecular dynamics study
2005 Chillemi, G; Fiorani, P; Castelli, S; Bruselles, A; Benedetti, Pietro; Desideri, A.
Expression of Human DNA Topoisomerase I in Yeast Cells Lacking Yeast Topoisomerase I: Restoration of Sensitivity of the Cells to the Antitumor Drug Campothecin.
1989 Bjornsti, M. A.; Benedetti, Pietro; Viglianti, G. A; Wang, J. C.
Holoenzyme assembly and ATP-mediated conformational dynamics of topoisomerase VI
2007 Corbett, Kd; Benedetti, Pietro; Berger, Jm
Il racconto delle origini. Dal Big bang alla vita.
2005 Benedetti, Pietro; Benacchio, L.; Rasotto, MARIA BERICA
In vitro catenation and decatenation of DNA and a novel ATP-dependent topoisomerase.
1980 BALDI M., I; Benedetti, Pietro; Mattoccia, E; TOCCHINI VALENTINI, G. P.
Increased camptothecin toxicity in mammalian cells expressing Saccharomyces cerevisiae DNA topoisomerase I.
1998 Hann, C; E. V. A. N. S., . D. L; Fertala, J; Benedetti, Pietro; B. J. O. R. N. S. T. I., . M. A.
Inhibition of ErbB-2 mitogenic and transforming activity by RALT, a mitogen-induced signal transducer which binds to the ErbB-2 kinase domain
2000 Fiorentino, L; Pertica, C; Fiorini, M; Talora, C; Crescenzi, M; Castellani, L.; Alema', S; Benedetti, Pietro; Segatto, O.
Locking the DNA topoisomerase I protein clamp inhibits DNA rotation and induces cell lethality
2003 M. H., Woo; Losasso, Carmen; H., Guo; Pattarello, Luca; Benedetti, Pietro; M. A., Bjornsti
Mechanisms regulating cellular responses to DNA topoisomerase I-targeted agents
2012 Benedetti, Pietro; Bjornsti, M. A.
Molecular Dissection of a Protein SopB Essential for E.coli F Plasmid Partition.
1996 Hanai, R.; Liu, R; Benedetti, Pietro; Caron, P. R; Lynch, ; A. S., AND WANG; J., C.