SARNO, STEFANIA
 Distribuzione geografica
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Continente #
NA - Nord America 9.999
AS - Asia 4.939
EU - Europa 1.985
AF - Africa 788
SA - Sud America 692
Continente sconosciuto - Info sul continente non disponibili 96
OC - Oceania 73
Totale 18.572
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Nazione #
US - Stati Uniti d'America 9.522
SG - Singapore 1.606
CN - Cina 896
VN - Vietnam 683
HK - Hong Kong 523
BR - Brasile 381
IT - Italia 283
FI - Finlandia 235
DE - Germania 218
BD - Bangladesh 179
IN - India 162
FR - Francia 156
SE - Svezia 119
UA - Ucraina 118
GB - Regno Unito 95
RU - Federazione Russa 77
PL - Polonia 70
CA - Canada 69
TR - Turchia 65
IQ - Iraq 60
PH - Filippine 60
AR - Argentina 58
JP - Giappone 54
NL - Olanda 49
ID - Indonesia 45
VE - Venezuela 45
MX - Messico 44
ZA - Sudafrica 44
PK - Pakistan 40
ES - Italia 38
TN - Tunisia 38
NP - Nepal 37
CO - Colombia 36
EG - Egitto 36
IE - Irlanda 36
SA - Arabia Saudita 36
CL - Cile 34
KE - Kenya 32
MA - Marocco 31
AL - Albania 30
AO - Angola 30
EC - Ecuador 30
HN - Honduras 29
UZ - Uzbekistan 29
CI - Costa d'Avorio 28
TT - Trinidad e Tobago 28
MY - Malesia 27
AT - Austria 26
JM - Giamaica 26
MR - Mauritania 26
PE - Perù 26
TZ - Tanzania 26
NI - Nicaragua 25
PY - Paraguay 25
CW - ???statistics.table.value.countryCode.CW??? 24
KZ - Kazakistan 24
MU - Mauritius 24
RO - Romania 24
TJ - Tagikistan 24
BB - Barbados 23
GA - Gabon 23
GT - Guatemala 23
IL - Israele 23
LC - Santa Lucia 23
CV - Capo Verde 22
GE - Georgia 22
JO - Giordania 22
LB - Libano 22
MN - Mongolia 22
PR - Porto Rico 22
PT - Portogallo 22
SI - Slovenia 22
DZ - Algeria 21
ET - Etiopia 21
GF - Guiana Francese 21
LV - Lettonia 21
NC - Nuova Caledonia 21
AE - Emirati Arabi Uniti 20
AZ - Azerbaigian 20
BO - Bolivia 20
CZ - Repubblica Ceca 20
DK - Danimarca 20
DO - Repubblica Dominicana 20
GH - Ghana 20
HU - Ungheria 20
KG - Kirghizistan 20
MD - Moldavia 20
NE - Niger 20
PS - Palestinian Territory 20
TH - Thailandia 20
BE - Belgio 19
BY - Bielorussia 19
EE - Estonia 19
HR - Croazia 19
BZ - Belize 18
IR - Iran 18
LA - Repubblica Popolare Democratica del Laos 18
ME - Montenegro 18
NO - Norvegia 18
PA - Panama 18
Totale 17.681
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Città #
Ashburn 1.150
Fairfield 1.027
Singapore 971
Woodbridge 868
San Jose 790
Ann Arbor 621
Houston 550
Chandler 537
Hong Kong 465
Jacksonville 453
Wilmington 406
Seattle 364
Cambridge 354
Ho Chi Minh City 187
Princeton 177
Hanoi 160
Beijing 158
Boardman 153
San Diego 130
Los Angeles 127
Helsinki 119
Santa Clara 115
Des Moines 94
Lauterbourg 80
Nanjing 67
New York 66
Padova 60
Guangzhou 56
Dong Ket 53
Chicago 48
Roxbury 44
Bytom 39
São Paulo 39
Da Nang 38
Dublin 33
Tokyo 33
Haiphong 32
Munich 32
Orem 30
Nairobi 28
Abidjan 27
Medford 26
Tashkent 26
Managua 25
Hebei 24
Luanda 24
Nanchang 24
Rome 24
Chennai 23
Dushanbe 23
Libreville 23
Shanghai 23
Shenyang 23
Amman 22
Baghdad 22
Buffalo 22
Dallas 22
Falls Church 22
Frankfurt am Main 22
Ulan Bator 22
Bridgetown 21
Castries 21
London 21
Montreal 21
Noumea 21
Tianjin 21
Vienna 21
Addis Ababa 20
Baku 20
Nouakchott 20
Praia 20
Changsha 19
Dar es Salaam 19
Willemstad 19
Cayenne 18
Salt Lake City 18
San Francisco 18
Accra 17
Johannesburg 17
Panama City 17
Harare 16
Kampala 16
Kigali 16
Kingston 16
Kuala Lumpur 16
Milan 16
Niamey 16
Phnom Penh 16
Podgorica 16
Tirana 16
Andorra la Vella 15
Atlanta 15
Lima 15
Norwalk 15
Riga 15
Tbilisi 15
Turku 15
Warsaw 15
Bishkek 14
Brooklyn 14
Totale 11.920
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Nome #
ATP Site-Directed Inhibitors of Protein Kinase CK2: An Update 340
Design, validation and efficacy of bisubstrate inhibitors specifically affecting ecto-CK2 kinase activity 304
Tetrabromocinnamic acid (TBCA) and related compounds represent a new class of specific protein kinase CK2 inhibitors 298
Basic residues in the 74-83 and 191-198 segments of protein kinase CK2 catalytic subunit are implicated in negative but not in positive regulation by the beta-subunit 292
Protein kinase CK2 phosphorylates and upregulates Akt/PKB 286
Benextramine and derivatives as novel human monoamine oxidases inhibitors: an integrated approach 279
Biochemical and three-dimensional-structural study of the specific inhibition of protein kinase CK2 by [5-oxo-5,6-dihydroindolo-(1,2-a)quinazolin-7-yl]acetic acid (IQA) 278
Inhibition of Protein Kinase CK2 by Flavonoids and Tyrphostins. A Structural Insight. 275
The Selectivity of CK2 Inhibitor Quinalizarin: A Reevaluation 272
Protein kinase CK2: a potential therapeutic target for diverse human diseases 270
Quinalizarin as a potent, selective and cell-permeable inhibitor of protein kinase CK2 269
Identification of ellagic acid as potent inhibitor of protein kinase CK2: a successful example of a virtual screening application. 264
Exploiting the repertoire of CK2 inhibitors to target DYRK and PIM kinases 258
Biochemical analysis of the interactions between the proteins involved in the [FeFe]-hydrogenase maturation process. 250
Inspecting the structure-activity relationship of protein kinase CK2 inhibitors derived from tetrabromo-benzimidazole 249
Cell-permeable dual inhibitors of protein kinases CK2 and PIM-1: structural features and pharmacological potential 245
The lysine-specific demethylase 1 is a novel substrate of protein kinase CK2 240
Inhibition of protein kinase CK2 by condensed polyphenolic derivatives. An in vitro and in vivo study 230
Development and exploitation of CK2 inhibitors 227
The Replacement of ATP by the Competitive Inhibitor Emodin Induces Conformational Modifications in the Catalytic Site of Protein Kinase CK2 226
New potential peptide therapeutics perturbing CK1δ/α-tubulin interaction 221
Role of CK2 inhibitor CX-4945 in anti-cancer combination therapy - potential clinical relevance 221
Autophosphorylation at the regulatory beta subunit reflects the supramolecular organization of protein kinase CK2 220
Structural features underlying the selectivity of the kinase inhibitors NBC and dNBC: role of a nitro group that discriminates between CK2 and DYRK1A 220
A novel class of selective CK2 inhibitors targeting its open hinge conformation 220
The selectivity of inhibitors of protein kinase CK2: an update 216
A comparative analysis of the photosensitized inhibition of growth-factor regulated protein kinases by hypericin-derivatives 215
Isoform specific phosphorylation of p53 by protein kinase CK1 214
A multifunctional network of basic residues confers unique propertiers to protein kinase CK2 213
Bovine prion protein as a modulator of protein kinase CK2 209
Cooperative modulation of protein kinase CK2 by separate domains of its regulatory beta-subunit 208
Acidophilic character of yeast piD261/Bud32, a putative ancestor of eukaryotic protein kinases 208
Superiority of PLK-2 as α-synuclein phosphorylating agent relies on unique specificity determinants. 206
Hydrophobic Derivatives of Glycopeptide Antibiotics as Inhibitors of Protein Kinases 205
The ATP-binding site of protein kinase CK2 holds a positive electrostatic area and conserved water molecules 205
Inhibitors of protein kinase CK2: structural aspects 204
The p23 co-chaperone protein is a novel substrate of CK2 in Arabidopsis 204
Mutational analysis of residues implicated in the interaction between protein kinase CK2 and peptide substrates 204
Protein kinase CK2 as a druggable target 202
How can a traffic light properly work if it is always green? The paradox of CK2 signaling 202
Features and potentials of ATP-site directed CK2 inhibitors 200
Does CK2 start chromatin condensation in mitotic phase? 200
A complex signaling network involving protein kinase CK2 is required for hepatitis C virus core protein-mediated modulation of the iron-regulatory hepcidin gene expression 199
Cystic fibrosis transmembrane regulator fragments with the Phe508 deletion exert a dual allosteric control over the master kinase CK2 198
Unprecedented Selectivity and Structural Determinants of a New Class of Protein Kinase CK2 Inhibitors in Clinical Trials for the Treatment of Cancer 198
Ser/Thr phosphorylation of hematopoietic specific protein 1 (HS1) - Implication of protein kinase CK2 197
Structural features underlying selective inhibition of protein kinase CK2 by ATP site-directed tetrabromo-2-benzotriazole 195
Toward the rational design of protein kinase casein kinase-2 inhibitors 194
Optimization of protein kinase CK2 inhibitors derived from 4,5,6,7-tetrabromobenzimidazole 192
Extraordinary pleiotropy of protein kinase CK2 revealed by weblogo phosphoproteome analysis 191
Autocatalytic tyrosine-phosphorylation of protein kinase CK2 alpha and alpha' subunits: implication of Tyr182 187
SPECIFICITY OF THE POLYCATION-STIMULATED (TYPE-2A) AND ATP,MG- DEPENDENT (TYPE-1) PROTEIN PHOSPHATASES TOWARD SUBSTRATES PHOSPHORYLATED BY P34CDC2 KINASE 182
Regulatory subunit of protein kinase CK2 contributes to the recognition of the substrate consensus sequence. A study with an eIF2 beta-derived peptide 181
The yeast cyclin-dependent kinase inhibitor Sic1 and mammalian p27(Kip1) are functional homologues with a structurally conserved inhibitory domain 181
Selectivity of 4,5,6,7-tetrabromo-benzotriazole, an ATP site-directed inhibitor of protein kinase CK2 ("casein kinase-2") 180
The protein kinase CK2 facilitates repair of chromosomal DNA single-strand breaks 179
Unique features of HIV-1 Rev protein phosphorylation by protein kinase CK2 ('casein kinase-2') 179
Discrimination between the activity of protein kinase CK2 holoenzyme and its catalytic subunits 177
Modulation of protein kinase CK2 activity by fragments of CFTR encompassing F508 may reflect functional links with cystic fibrosis pathogenesis 176
Programmed cell death protein 5 (PDCD5) is phosphorylated by CK2 in vitro and in 293T cells 174
Cystic fibrosis transmembrane regulator fragments with the Phe508 deletion exert a dual allosteric control over the master kinase CK2. 174
POLYAMINES AS NEGATIVE REGULATORS OF CASEIN KINASE-2 - THE PHOSPHORYLATION OF CALMODULIN TRIGGERED BY POLYLYSINE AND BY THE ALPHA[66-86] PEPTIDE IS PREVENTED BY SPERMINE 169
Aberrant Signalling by Protein Kinase CK2 in Imatinib-resistant Chronic Myeloid Laeukemia Cells 169
Eukaryotic translation-initiation factor eIF2β binds to protein kinase CK2: Effects on CK2α activity 166
Tyrosine versus serine/threonine phosphorylation by protein kinase casein kinase-2 - A study with peptide substrates derived from immunophilin Fpr3 164
Structure-activity relationship of protein kinase CK2 inhibitors with different scaffolds 158
RAPID STIMULATION OF SER THR PROTEIN-KINASES FOLLOWING TREATMENT OF SWISS 3T3 CELLS WITH BOMBESIN - INVOLVEMENT OF CASEIN KINASE-2 IN THE SIGNALING PATHWAY OF BOMBESIN 153
The crystal structure of the complex of Zea mays alpha subunit with a fragment of human beta subunit provides the clue to the architecture of protein kinase CK2 holoenzyme. 152
Inhibition of protein kinase CK2 by anthraquinone-related compounds. A structural insight 151
Mapping the residues of protein kinase CK2 alpha subunit responsible for responsiveness to polyanionic inhibitors 150
pCMB treatment reveals the essential role of cysteinyl residues in conferring functional competence to the regulatory subunit of protein kinase CK2 148
CK2: a protein kinase in need of control 146
Characterization of the oligomeric states of the CK2 alpha2beta2 holoenzyme in solution 146
Biochemical evidence that the N terminal segment of the alpha-subunit and the ß-subunit play interchangeable roles in the activation of protein kinase CK2 146
Hematopietic lineage cell specific protein 1 associates with and down-regulates protein kinase CK2. 145
HIV-1 Rev transactivator: a beta-subunit directed substrate and effector of protein kinase CK2 145
Expression of the Stp1 LMW-PTP and inhibition of protein CK2 display a cooperative effect on immunophilin Fpr3 tyrosine phosphorylation and Saccharomyces cerevisiae growth 145
Protein kinase CK2 catalyzes tyrosine phosphorylation in mammalian cells. 145
Physical dissection of the structural elements responsible for regulatory properties and intersubunit interactions of protein kinase CK2 beta-subunit 144
Structural features of protein kinase CK2. 139
Cross talk between protein kinase CK2 and eukaryotic translation initiation factor eIF2beta subunit. 139
Identification of new powerful and selectiveinhibitors of protein kinases CK1δ and CK2 bycomputer aided virtual screening and molecularderivatization of anthraquinone scaffolds 137
Rational design of new competitive inhibitors of human CK2 activity 136
Mass spectrometry analysis of a protein kinase CK2 beta subunit interactome isolated from mouse brain by affinity chromatography 135
Tyr-phosphorylation of protein kinase CK2 by Src related tyrosine kinases correlates with increased catalytic activity 130
The carboxy-terminal domain of Grp94 binds to protein kinase CK2 alpha but not to CK2 holoenzyme 129
Functional analysis of CK2beta-derived synthetic fragments 128
PHOSPHORYLATION OF SYNTHETIC FRAGMENTS OF INHIBITOR-2 OF PROTEIN PHOSPHATASE-1 BY CASEIN KINASE-1 AND KINASE-2 - EVIDENCE THAT PHOSPHORYLATED RESIDUES ARE NOT STRICTLY REQUIRED FOR EFFICIENT TARGETING BY CASEIN KINASE-1 127
Regulation of casein kinase-2 (CK2) by polyamines and other polycationic effectors" in Polyamines: Biological and Clinical Aspects 126
2-(Phenylamino)-7,8-dihydroquinazolin-5(6H)-one, a promising scaffold for MAO-B inhibitors with potential GSK3β targeting 119
Generation of mutants of CK2 alpha which are dependent on the beta-subunit for catalytic activity. 119
Unique activation mechanism of protein kinase CK2. The N-terminal segment is essential for constitutive activity of the catalytic subunit but not of the holoenzyme 114
Involvement of Protein Kinase CK2 in Imatinib-resistant Chronic Myeloid Leukemia Cells 113
Structural basis for selective inhibition of protein kinase CK2 by ATP site-directed ligands 113
Rational design of new competitive inhibitors of human CK2 activity 112
Mapping the Residues of Protein Kinase CK2 Implicated in Substrate Recognition: Mutagenesis of Conserved Basic Residues in the α-Subunit 104
Protein kinase CK2 mutants defective in substrate recognition - Purification and kinetic analysis 99
Molecular features of selective polyphenolic inhibitors of protein kinase CK2 94
null 14
Totale 18.572
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Categoria #
all - tutte 53.657
article - articoli 50.397
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 857
Totale 104.911
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2021/20221.404 32 138 257 105 42 105 56 159 53 30 185 242
2022/20231.081 189 127 9 180 132 189 1 64 114 13 51 12
2023/2024484 17 93 57 25 52 57 26 28 19 17 62 31
2024/20251.785 3 91 79 92 255 56 77 132 159 57 331 453
2025/20268.556 279 671 1.112 1.379 797 349 1.340 773 804 497 330 225
2026/2027267 267 0 0 0 0 0 0 0 0 0 0 0
Totale 18.572