NEGRO, ALESSANDRO
 Distribuzione geografica
Salva come PNG Salva come JPEG
Continente #
NA - Nord America 8.056
EU - Europa 1.356
AS - Asia 879
OC - Oceania 6
Continente sconosciuto - Info sul continente non disponibili 5
SA - Sud America 5
Totale 10.307
Salva come PNG Salva come JPEG
Nazione #
US - Stati Uniti d'America 8.041
CN - Cina 449
DE - Germania 356
SG - Singapore 300
FI - Finlandia 251
IT - Italia 247
UA - Ucraina 168
SE - Svezia 108
FR - Francia 101
GB - Regno Unito 77
VN - Vietnam 68
IE - Irlanda 25
IN - India 21
PK - Pakistan 19
CA - Canada 15
KR - Corea 14
NL - Olanda 9
AU - Australia 5
EU - Europa 5
AR - Argentina 4
RU - Federazione Russa 4
BG - Bulgaria 3
IR - Iran 2
TW - Taiwan 2
AT - Austria 1
BR - Brasile 1
CH - Svizzera 1
CZ - Repubblica Ceca 1
DK - Danimarca 1
HK - Hong Kong 1
IL - Israele 1
NO - Norvegia 1
NZ - Nuova Zelanda 1
PH - Filippine 1
RO - Romania 1
SK - Slovacchia (Repubblica Slovacca) 1
TR - Turchia 1
Totale 10.307
Salva come PNG Salva come JPEG
Città #
Fairfield 1.018
Woodbridge 844
Jacksonville 810
Ann Arbor 675
Chandler 639
Houston 622
Ashburn 531
Wilmington 442
Seattle 379
Cambridge 337
Princeton 275
Singapore 231
Beijing 111
Des Moines 102
Nanjing 99
San Diego 99
Helsinki 95
Padova 91
Medford 86
Boardman 76
Roxbury 70
Dong Ket 68
Guangzhou 43
Santa Clara 41
Nanchang 33
Shenyang 31
Norwalk 29
Redwood City 28
Jiaxing 25
New York 25
Hebei 23
Changsha 21
Nürnberg 21
Dublin 20
Karachi 18
Tianjin 18
Indiana 12
Seoul 11
Washington 11
Munich 10
Venice 10
Vicenza 10
London 9
Montréal 9
Verona 9
Falls Church 8
Milan 8
Dallas 7
Kharkiv 7
Rome 7
Tappahannock 7
Chicago 6
Detroit 6
Jinan 5
Kilburn 5
Rockville 5
Amsterdam 4
Edinburgh 4
Federal 4
Los Angeles 4
Ogden 4
Parma 4
San Francisco 4
Zhengzhou 4
Aprilia 3
Fontanelle 3
Giustino 3
Groningen 3
Haikou 3
Lanzhou 3
Lappeenranta 3
Martellago 3
Phoenix 3
Portici 3
Redmond 3
Salgareda 3
Sofia 3
Acton 2
Borås 2
Buffalo 2
Cagliari 2
Camisano 2
Cava de' Tirreni 2
Centro 2
Cherasco 2
Chiswick 2
Cleveland 2
Costa Mesa 2
Hefei 2
Hounslow 2
Islington 2
Kunming 2
Lincoln 2
Lonato 2
Marghera 2
Mcallen 2
Melbourne 2
Mestrino 2
Napoli 2
Ningbo 2
Totale 8.355
Salva come PNG Salva come JPEG
Nome #
α-Synuclein Controls Mitochondrial Calcium Homeostasis by Enhancing Endoplasmic Reticulum-Mitochondria Interactions. 204
In vitro evaluation of TAT-OP1 osteogenic properties and prospects for in vivo applications. 188
Aggregation/fibrillogenesis of recombinant human prion protein and Gerstmann-Straussler-Scheinker disease peptides in the presence of metal ions. 167
Protein disulfide isomerase and glutathione are alternative substrates in the one Cys catalytic cycle of glutathione peroxidase 7 146
Human Doppel and prion protein share common membrane microdomains and internalization pathways 127
A cationic tetrapyrrole inhibits toxic activities of the cellular prion protein 123
In vitro assessment of TAT - Ciliary Neurotrophic Factor therapeutic potential for peripheral nerve regeneration 120
Copper II binding to the human doppel protein may mark its functional diversity from the prion protein 119
Selective and efficient immunoprecipitation of the disease-associated form of the prion protein can be mediated by nonspecific interactions between monoclonal antibodies and scrapie-associated fibrils 119
The intracellular delivery of TAT-aequorin reveals calcium-mediated sensing of environmental and symbiotic signals by the arbuscular mycorrhizal fungus Gigaspora margarita 118
Enhanced parkin levels favor ER-mitochondria crosstalk and guarantee Ca(2+) transfer to sustain cell bioenergetics. 118
Structural and mutational analyses of protein-protein interactions between transthyretin and retinol-binding protein 117
Bovine prion protein as a modulator of protein kinase CK2 115
The Parkinson's Disease-Related Protein DJ-1 Protects Dopaminergic Neurons in vivo and Cultured Cells from Alpha-Synuclein and 6-Hydroxydopamine Toxicity 114
Effects of in vivo applications of peripheral blood-derived mesenchymal stromal cells (PB-MSCs) and platlet-rich plasma (PRP) on experimentally injured deep digital flexor tendons of sheep. 113
Crystal structure and refolding properties of the mutant F99S/M153T/V163A of the Green Fluorescent Protein 107
Superiority of PLK-2 as α-synuclein phosphorylating agent relies on unique specificity determinants. 107
Caratterizzazione di peptidi ACE-inibitori prodotti ad opera di batteri proteolitici impiegati per la realizzazione di latte-fermentati. 105
TAT-mediated aequorin transduction: an alternative approach for effective calcium measurements in plant cells 105
The metabolism and imaging in live cells of the bovine prion protein in its native form or carrying single amino acid substitutions 104
The prion protein and its paralogue Doppel affect calcium signaling in Chinese hamster ovary cells 100
Ciliary neurotrophic factor infused intracerebroventricularly shows reduced catabolic effects when linked to the TAT protein transduction domain. 99
Comparison in vivo applications between peripheral blood-derived mesenchymal stromal cells (PB-MSCs) and platlet-rich plasma (PRP) in injured tendons of sheep 99
Tools to discriminate between targets of CK2 vs PLK2/PLK3 acidophilic kinases. 97
Cloning and expression of human ciliary neurotrophic factor 96
A Novel Prion Protein-Tyrosine Hydroxylase Interaction 94
An antipsychotic drug exerts anti-prion effects by altering the localization of the cellular prion protein 94
Recombinant human TAT-OP1 to enhance NGF neurogenic potential: preliminary studies on PC12 cells 94
Modulation of the structural integrity of helix F in apomyoglobin by single amino acid replacements 86
Hydrogel-based delivery of Tat-fused protein Hsp70 protects dopaminergic cells in vitro and in a mouse model of Parkinson’s disease 86
Production and characterization of recombinant rat brain-derived neurotrophic factor and neurotrophin-3 from insect cells 85
In Vivo Applications of Mesenchymal Stem Cells and Platelet-Rich Plasma to Improve Tendon Regeneration in Sheep. 85
DJ-1 modulates a-synuclein aggregation state in a cellular model of oxidative stress: Relevance for Parkinson’s disease and involvement of HSP-70. 84
Protein misfolding in Alzheimer's and Parkinson's disease: genetics and molecular mechanisms 84
Recombinant human ciliary neurotrophic factor alters the threshold of hippocampal pyramidal neuron sensitivity to excitotoxin damage: synergistic effects of monosialogangliosides. 83
Nerve growth factor antibodies recognize neurotrophin-3 83
Identifying novel thrombin interactions: alpha-synuclein binds to thrombin exosites and inhibits thrombin-mediated platelet aggregation 83
Ciliary neurotrophic factor-induced gene expression in human neuroblastoma cell lines 82
The use of reverse-phase high-performance liquid chromatography and precolumn derivatization with dansyl chloride for quantitation of specific amino acids in collagen and elastin 81
Temperature-dependent functional expression of a plant K+ channel in mammalian cells 80
CNTF up-regulation of TIMP-2 in neuroblastoma cells 79
The effect of the osmolyte trimethylamine N-oxide on the stability of the prion protein at low pH 79
Neurotrophins rescue cerebellar granule neurons from oxidative stress-mediated apoptotic death: selective involvement of phosphatidylinositol 3-kinase and the mitogen-activated protein kinase pathway. 78
Establishment and characterization of a CHO cell line producing a secreted form of human ciliary neurotrophic factor: neuroprotective effects of the recombinant protein 77
Rational Design of Allosteric and Selective Inhibitors of the Molecular Chaperone TRAP1 77
Synthesis and purification of biologically active rat brain derived neurotrophic factor from Escherichia coli 76
Production, characterization and cytotoxic properties of a diphtheria toxin-ciliary neurotrophic factor fusion protein. 76
A comparative assessment of the effectiveness of adult stem cell (MSCS) and platenet rich plasma (PRP) applied on tendon lesions: preliminary results. 76
Role of Lipid Rafts and GM1 in the Segregation and Processing of Prion Protein 76
Expression study on D123 gene product: evidence for high positivity in testis 74
Tat-MyoD fused proteins, together with C2c12 conditioned medium, are able to induce equine adult mesenchimal stem cells towards the myogenic fate 74
Apoptosis of spinal interneurons induced by sciatic nerve axotomy in the neonatal rat is counteracted by nerve growth factor and ciliary neurotrophic factor 73
Susceptibility of the prion protein to enzymatic phosphorylation 73
The Parkinson disease related protein DJ-1 counteracts mitochondrial impairment induced by the tumor suppressor protein p53 by enhancing Endoplasmic Reticulum-mitochondria tethering. 73
Biochemical immunohistochemical and immuno-electron microscopic characterization of monoclonal antibodies recognizing species-specific prion protein 72
Type IV collagenolytic activity linkage with the metastatic phenotype induced by ras transfection. 72
Ganglioside GM1 cooperates with brain derived neurotrophic factor to protect dopaminergic neurons from 6-hydroxydopamine-induced degeneration 71
The Small Heat Shock Protein HspB8: Role in Nervous System Physiology and Pathology 71
Advantages and limitations of a supernegative GFP in facilitating MyoD intracellular tracking 71
Nerve growth factor (NGF) receptors in a central nervous system glial cell line: upregulation by NGF and brain-derived neurotrophic factor 70
Synthesis, cytotoxic properties and effects on early and late gene induction of a chimeric diphtheria toxin-leukemia-inhibitory factor protein 70
Ciliary neurotrophic factor fused to a protein transduction domain retains full neuroprotective activity in the absence of cytokine-like side effects. 70
Vectors for expression of ngf in eukaryotic cells. 70
The fact of a polyoma early promoter plasmid in transgenic mice. 69
A comparative analysis of the cell properties of Dpl and PrPc 68
Structure-function studies of human ciliary neurotrophic factor 66
Production and characterization of monoclonal antibodies to human ciliary neurotrophic factor with defined epitope recognition 64
Sonic Hedgehog (Shh) induces proliferation of neural progenitor cells isolated from rat postnatal cerebellum 64
Controlled Drug Delivery Microspheres for Osteogenic Differentiation 63
Production and characterization of recombinant rat brain-derived neurotrophic factor and neurotrophin-3 from insect cells 63
Synthesis and refolding of human TIMP-2 from E.coli, with specific activity for MMP-2. 62
Effects of systemic administration of ciliary neurotrophic factor on Bax and Bcl-2 proteins in the lumbar spinal cord of neonatal rats after sciatic nerve transection 60
Tyrosine and serine phosphorylation of alpha-synuclein have opposing effects on neurotoxicity and soluble oligomer formation. 60
Doppel and PrPC co-immunoprecipitate in detergent-resistant membrane domains of epithelial FRT cells 60
Expression of Prion proten and Doppel affects Ca2+ signalling 59
Transient expression of type IV collagenolytic metalloproteinase by human mononuclear phagocytes 59
The nuclear import of the transcription factor MyoD is reduced in mesenchymal stem cells grown in a 3D micro-engineered niche 59
The complete mature bovine prion protein highly expressed in Escherichia coli: biochemical and structural studies 58
A comparative analysis of the properties of Dpl and PrPC. 58
Novel Interactions of Thrombin 58
In vivo application of autologous Mesenchymal stem cells (MSC) and Platelet rich plasma (PRP) in collagenase I experimental lesion. Clinical oucomes at one and four months. 57
ACE-inhibition and imunomodulant activity of milk fermented with lactic acid bacteria isolated from traditional Italian dairy products 56
Analysis of the effects of alpha-synuclein on mitochondrial Ca2+ homeostasis 56
Intracellular delivery of Neuroglobin using HIV-1 TAT protein transduction domain fails to protect against oxygen and glucose deprivation 56
Hirudeco: A Hirudin Mutant Containing the Functional RGD-Loop of Decorsin 55
Ciliary Neurotrophic factor promotes survival of neonatal rat islets via the BLC-2 antiapoptotic patway 55
The SIRT1 activator resveratrol protects SK-N-BE cells from oxidative stress and against toxicity caused by alpha-synuclein or amyloid-beta (1-42) peptide. 55
cDNA cloning and characterization of PD1: a novel human testicular protein with different expressions in various testiculopathies 55
DJ-1 is a multifunctional protein: its possible role in the control of cellular Ca2+ homeostasis. 54
Sonic hedgehog (SHH) induces proliferation of neural progenitor cells isolated from rat postata cerebellum. 53
Cloning of 3-hydroxyaanthranilic acid dioxygenase in E coli: charcterization of the purified enzyme and its in vitro inhibition by Zn 52
Functional expression of plant potassium channels in mammalian cells 52
Identification, sequencing and mutagenesis of the gene for a D-carbamoylase from Agrobacterium radiobacter 52
Protective effect of TAT-delivered alpha synuclein: relevance of the C-terminal domain and involvement of HSP70 52
Fermented milks from Enterococcus faecalis TH563 and Lactobacillus delbrueckii ssp. bulgaricus LA2 manifest different degrees of ACE-inhibitory and immunomodulatory activities 51
Synthesis and purification of truncated and mutein forms of human ciliary neuronotrophic factor. 51
Organic polyanions act as complexants of prion protein in soil 51
Structure-function studies of human ciliary neurotrophic factor. 51
Generation of a alpha-synuclein-based rat model of Parkinson's disease 51
The role of phosphorylation in synuclephaties: focus on Parkinson's Disease 49
Totale 8.123
Salva come PNG Salva come JPEG
Categoria #
all - tutte 33.563
article - articoli 25.442
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 173
patent - brevetti 1.041
selected - selezionate 0
volume - volumi 473
Totale 60.692
Salva come PNG Salva come JPEG


Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2019/20201.542 0 0 33 136 174 163 145 220 170 247 133 121
2020/20211.562 63 126 68 181 112 148 12 167 230 112 208 135
2021/20221.613 20 249 220 87 81 93 55 167 68 27 215 331
2022/20231.494 326 127 22 154 265 211 5 92 173 18 76 25
2023/2024667 22 111 82 65 56 67 33 28 20 16 79 88
2024/2025409 6 286 117 0 0 0 0 0 0 0 0 0
Totale 10.353